In this scenario, the student is tasked with answering a doctor's questions about starting a breastfeeding patient on medication to treat hyperthyroidism.
Please ensure that this scenario and mark scheme align with the most up-to-date UK NICE guidelines and the BNF when using it for your OSCE assessment.
A student pharmacist and an actor playing the role of a trainee doctor are required.
Hyperthyroidism
Pregnancy
Beta Blockers
Lab Results
You are a pharmacist working in a community pharmacy. A local trainee GP has come to the pharmacy seeking advice on prescribing medication for hyperthyroidism.
You are expected to gather relevant information and respond to their questions appropriately.
To do
Gather essential patient details, including medical history, current medications, allergies, and lifestyle factors relevant to the scenario
Offer clear, evidence-based advice to the GP on potential next steps, including management options or further diagnostic testing.
You have 8 minutes.
You have access to the BNF.
Your name is Dr. Jun Devan (Joon, Dee-vahn).
You are a trainee GP.
Opening statement: “Hi, my name is Doctor Devan.I have some questions about a patient who a specialist has recommended me to commence on carbimazole, but who is currently breastfeeding."
Patient details:
Provide this information when prompted.
Name: Jessica Arden (Jess-ih-kuh, Ar-den)
Age: 29
Gender:
“Female.”
Symptoms:
“She has had a 1-month history of palpitations, hair loss, diarrhoea, and anxiety.”
Drug history:
“Not on any long-term prescription medication.”
“She does take paracetamol when required for migraines.”
Past medical history:
“4-year history of Migraines.”
Information:
“Currently breastfeeds a 6-month-old baby.”
“Mentioned is hoping to try for another baby soon.”
“She is trying to conceive within the following 6 months”
Test results
“I have her test results with me too." – provide these 3 minutes in if not prompted.
Thyroid Function Test Results | Patient Results | Reference Range | Levels |
TSH | 0.3mU/L | 0.5-5.7mU/L | Low |
fT4 | 180nanomol/L | 70-140nanomol/L | High |
fT3 | 200pmol/L | 60-180pmol/L | High |
Questions:
“Can I give carbimazole to a breast-feeding patient?”
ONLY ask questions 2-3 if the student asks about whether the patient is at risk of pregnancy/needs contraception when taking carbimazole. (any mention of contraindication during pregnancy).
“She is planning for another pregnancy so what medication can I give her?"
“Will she need any monitoring on that?”
“The specialist recommended I should prescribe a beta-blocker in patients with hyperthyroidism, do you know why?”
“Which beta-blocker would you recommend and what dose?”
Any criteria marked in red must be met to pass this station.
Referral Criteria for Hyperthyroidism:
Emergency A&E Referral:
Thyroid Storm:High fever, severe agitation, rapid heart rate, or confusion requires immediate attention.
Severe Cardiac Issues:Sudden chest pain or severe shortness of breath, indicating potential heart attack or failure.
Neurological Symptoms:Confusion, seizures, or unconsciousness may point to a severe complication.
Urgent GP Appointment Referral:
Heart Symptoms:Palpitations, chest pain, shortness of breath, or irregular heartbeats. These could suggest complications like atrial fibrillation.
Eye Problems:Eye pain, redness, swelling, bulging eyes, double vision, or vision changes could indicate Graves' ophthalmopathy.
Pregnancy:If pregnant or planning pregnancy with symptoms of hyperthyroidism, due to risks like preterm birth or pre-eclampsia.
Severe Symptoms:Rapid weight loss, significant tremors, or extreme fatigue suggesting uncontrolled hyperthyroidism.
NHS, 2024.Overactive thyroid (hyperthyroidism) - Complications. Available at:https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/complications/[Accessed 1 September 2024].
NICE, 2024.Hyperthyroidism. [online] Available at:https://cks.nice.org.uk/topics/hyperthyroidism/[Accessed 24 September 2024].
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