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Switching Antidepressants: Advising a Patient on Cross-Tapering from Sertraline to an Alternative Agent
By Billy Ip • July 25, 2026 • Last reviewed: 17/08/2026 •

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Summary Intermediate

In this scenario, a 32-year-old patient with moderate depression presents to the pharmacy having experienced intolerable side effects on Sertraline. The student must counsel the patient on safe antidepressant switching, including cross-tapering principles and monitoring requirements in line with NICE CG90.

You will need a student pharmacist and an actor for this OSCE station.

Student Instructions

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